About Collagenase SANTYL® Ointment

SANTYL® Ointment – Continuous, Active Micro-Debridement
SANTYL® Ointment is a Health Canada approved active enzymatic therapy that continuously removes necrotic tissue from wounds at the microscopic level.
This works to free the wound bed of microscopic cellular debris, allowing granulation to proceed and epithelialization to occur.1-3
SANTYL® Ointment contains 250 collagenase units per gram of white petrolatum USP. The enzyme collagenase is derived from the fermentation by Clostridium hystolyticum.
SANTYL® Ointment is appropriate for both initial debridement and continuous debridement after sharp or surgical debridement.
The SANTYL® Ointment advantage is its continuous, active debridement. Unlike macroscopic methods of debridement (sharp and surgical), SANTYL® Ointment continuously removes necrotic tissue, maintaining a clean wound bed. By taking an active approach instead of a passive one (e.g., autolytic debridement), SANTYL® Ointment enables debridement of chronic wounds, even for geriatric patients and those with compromised immune status.1,2
SANTYL® Ointment is indicated for the debridement of 4-7:
- Pressure ulcers
- Diabetic ulcers
- Venous leg ulcers
- Severely burned areas
- SANTYL® Ointment is contraindicated in patients who have shown local or systemic hypersensitivity to collagenase
Effectiveness in Clinical Studies
SANTYL® Ointment has been proven clinically efficacious in a number of studies in a variety of wound types4-16:
- Demonstrated superiority to placebo in the debridement of dermal ulcers
- Demonstrated superiority to standard antimicrobial therapy alone and combination with topical antimicrobial therapy in the debridement of severe burns
- Well tolerated in the debridement of both soft tissue ulcers and severe burns
MOA Video
SANTYL® is a registered trademark of Healthpoint Biotherapeutics. Healthpoint Biotherapeutics and design is a registered trademark of Healthpoint Biotherapeutics.
© 2010 Healthpoint Canada ULC. All rights reserved.
The information on this site is intended for customers, patients, and healthcare professionals in Canada only. All information, including the Prescribing Information for Collagenase SANTYL® Ointment, abides by the laws, regulatory requirements, and medical practices for Canada only and may not be appropriate for use outside of Canada.
© 2010 Healthpoint Canada ULC. All rights reserved.
The information on this site is intended for customers, patients, and healthcare professionals in Canada only. All information, including the Prescribing Information for Collagenase SANTYL® Ointment, abides by the laws, regulatory requirements, and medical practices for Canada only and may not be appropriate for use outside of Canada.